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    A study published in Neurobiology of Disease () investigated the link between neuroinflammation, gut microbiota changes, and butyrate depletion in Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Neuroinflammation plays a key role in AD progression, and free water (FW) imaging, which measures extracellular water content, serves as a marker for this process.…

A recent study led by Jun Kunisawa from the National Institutes of Biomedical Innovation, Japan, explores the relationship between high barley consumption, natto intake, and gut microbiota composition in non-obese individuals. Barley, rich in β-glucan, is known for its potential role in obesity prevention. Since dietary fiber is metabolized by gut microbiota, researchers investigated the…

Sarcopenia, an age-related muscle disorder, increases the risk of adverse clinical outcomes, but current treatment options are limited. Recent research highlights the potential role of gut microbiota in sarcopenia. The study compared gut microbiota and metabolites in older adults with and without sarcopenia, followed by fecal microbiota transplantation (FMT) in mice to investigate causality. Specific…

Researchers from the University of Michigan identified sulfur-producing bacteria as potential contributors to persistent symptoms in Crohn’s disease patients, even in remission without active inflammation. Microbiome Connection: Patients with lingering symptoms showed a significant increase in these bacteria within their gut microbiome. Role of Sulfur Compounds: These bacteria produce hydrogen sulfide, which can disrupt intestinal permeability and…