Category: Latest News

Altered Gut Microbiota, Reduced Butyrate, and Increased Gray Matter Free Water in Alzheimer’s and MCI Patients

Posted on by admin
    A study published in Neurobiology of Disease () investigated the link between neuroinflammation, gut microbiota changes, and butyrate depletion in Alzheimer’s disease (AD) and mild cognitive impairment (MCI). Neuroinflammation plays a key role in AD progression, and free water (FW) imaging, which measures extracellular water content, serves as a marker for this process.…

Brewing Gut Health How Coffee Consumption Shapes the Microbiome and Boosts Beneficial Bacteria

Posted on by admin
A recent study published in Nature Microbiology explores the relationship between coffee consumption and the human gut microbiome. Researchers found a significant association between coffee intake and the presence of Lawsonibacter asaccharolyticus, a bacterial species recently isolated from the human intestine (Nature Microbiology, 2024). Key Findings Association with Lawsonibacter asaccharolyticus: Higher coffee consumption correlates with…

Barley and Natto Consumption Linked to Beneficial Gut Bacteria in Non-Obese Individuals

Posted on by admin
A recent study led by Jun Kunisawa from the National Institutes of Biomedical Innovation, Japan, explores the relationship between high barley consumption, natto intake, and gut microbiota composition in non-obese individuals. Barley, rich in β-glucan, is known for its potential role in obesity prevention. Since dietary fiber is metabolized by gut microbiota, researchers investigated the…

The Hidden Architects of the Gut: Phage-Bacteria Dynamics in Early Childhood Development

Posted on by admin
A schematic of factors potentially accounting for high virus (phage) turnover in human guts. This study explores the dynamic relationship between bacteriophages (phages) and bacteria in the gut microbiome of infants and young children during their early years. Using metagenomic sequencing data from over 12,000 stool samples collected as part of the Environmental Determinants of Diabetes in…

The Role of Gut Microbiota in Sarcopenia and Potential Probiotic Treatments

Posted on by admin
Sarcopenia, an age-related muscle disorder, increases the risk of adverse clinical outcomes, but current treatment options are limited. Recent research highlights the potential role of gut microbiota in sarcopenia. The study compared gut microbiota and metabolites in older adults with and without sarcopenia, followed by fecal microbiota transplantation (FMT) in mice to investigate causality. Specific…

Mitochondrial Dysfunction Disrupts Microbiome, Leading to Crohn’s Disease

Posted on by admin
A new study published in Cell Host & Microbe reveals how mitochondrial dysfunction can disrupt the gut microbiome, contributing to the development of Crohn’s disease. Researchers from the Technical University of Munich (TUM), led by Prof. Dirk Haller, used intestinal organoids and a mouse model to investigate how mitochondrial impairment influences gut tissue and microbiome…

Key Findings: Sulfur-Producing Bacteria and Crohn’s Disease Symptoms

Posted on by admin
Researchers from the University of Michigan identified sulfur-producing bacteria as potential contributors to persistent symptoms in Crohn’s disease patients, even in remission without active inflammation. Microbiome Connection: Patients with lingering symptoms showed a significant increase in these bacteria within their gut microbiome. Role of Sulfur Compounds: These bacteria produce hydrogen sulfide, which can disrupt intestinal permeability and…

Link Between Gut Infections and Alzheimer’s Disease Uncovered

Posted on by admin
A new study led by researchers from Arizona State University (ASU) and Banner Alzheimer’s Institute has uncovered a compelling link between chronic gut infection by cytomegalovirus (HCMV)—a common virus—and the development of Alzheimer’s disease in a subset of individuals. The study suggests that in some cases, HCMV may persist in an active state in the…

Ketone Bodies: A Promising Link Between Metabolism, Mitochondrial Function, and Brain Health

Posted on by admin
An insightful study published in Cell Chemical Biology by researchers at the Buck Institute for Research on Aging has unveiled new roles for ketone bodies beyond their well-known function in energy production. The research focuses on the impact of these metabolites, particularly β-hydroxybutyrate, on brain function in the context of aging and Alzheimer’s disease. Key…