Microbial Modulation for Healthy Ageing of the Eye and Brain

Microbial Modulation for Healthy Ageing of the Eye and Brain

Aimee Parker, Quadram Institute, United Kingdom

Dr. Aimée Parker will explore how gut microbiota influences the aging process in the brain and eye, focusing on recent findings from fecal microbiota transplantation (FMT) studies. Her talk will highlight the role of microbial composition in neuroinflammation, retinal health, and systemic aging, raising critical questions about the potential of microbiome-based therapies for healthy aging.

Key Questions & Perspectives : 

1. Can We Reverse Aging Through Microbiota Modulation?

  • Can interventions like FMT or next-generation probiotics slow or even reverse neurodegeneration and vision decline?
  • What are the key microbial metabolites involved in protecting brain and eye health?

2. What Are the Limitations of Microbiota-Based Therapies?

  • Are long-term effects sustainable, or do microbiota changes revert over time?
  • Could altering the microbiome introduce unintended consequences, such as immune dysregulation or metabolic shifts?
  • How do individual genetic factors and diet influence microbiota-based interventions?

3. Can We Preserve Our Own Microbiome for Future Use?

  • Is fecal banking a viable strategy for aging prevention?
  • What challenges exist in storing and reintroducing one’s own youthful microbiota later in life?
  • Could personalized microbiome restoration become a mainstream clinical approach in aging medicine?

Future Perspectives

Dr. Parker’s session will encourage discussions on the future of microbiome-based longevity interventions, including FMT, engineered probiotics, and dietary strategies.

Microbiota in the Press & Media

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