Gut Microbiome and Cognitive Impairment in Ageing and Lessons from Systemic Inflammatory Diseases
Gaspar Perez Martinez, Institute of Agricultural Chemistry and Food Technology (IATA-CSIC), Spain
Key Points
- Is there an ageing clock in the gut microbiome?
- Cognitive decline is directly associated with age and the increase of inflammatory signals.
- Actually, cognitive impairment is bound to neuroinflammation which is triggered by systemic inflammation.
- In non-alcoholic fatty liver disease and cirrhosis, cognition is partially restored by the antibiotic rifaximin suggesting an involvement of the gut microbiota.
- Role of the gut metabolome and extracellular vesicles in the modulation of cognitive impairment
