Using Roseoflavin, a Natural Riboflavin Analogue, to Modify the Human Microbiota
The ISM is pleased to welcome Prof. Markus Egert, active member of the ISM scientific board, from Furtwangen University, Germany to Targeting Microbiota 2024 this October.
Prof. Egert will present a talk on "Using Roseoflavin, a Natural Riboflavin Analogue, to Modify the Human Microbiota".
Presentation Summary:
The antivitamin roseoflavin is a structural analogue and competitive inhibitor of riboflavin. Riboflavin is a precursor of the cofactors FMN and FAD, which are involved in various important cellular reactions.
The presentation will summarize the current state of a joint project, in which we examine the influence of roseoflavin on the structure of the human microbiota using cultivation-based as well as molecular approaches.
The project was inspired by a recent report that Streptococcus mutans, one of the most important cariogenic bacteria in the human mouth, appears to be auxotrophic for riboflavin and hence susceptible to roseoflavin.
About Markus Egert
Markus Egert is professor for Microbiology and Hygiene at Furtwangen University of Applied Sciences (Black Forest, Germany). His work aims at a deeper understanding of the structural and functional interactions of microbial communities with humans. He was one of the first researchers to apply the so-called RNA-based stable isotope probing technique (RNA-SIP) to intestinal ecosystem in order to identify prebiotics-degrading bacteria. In addition, he is known for his pioneering work on the microbiome of objects of daily use, such as kitchen sponges, spectacles and washing machines, and the hygienic relevance that goes with it.
Targeting Microbiota 2024 Speakers Line-up.
International Society of Microbiota
Targeting Microbiota 2024 Conference
October 14-15, 2024 - Malta
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