The microbiota, epigenome and transcriptome of colonic inflammation in inflammatory bowel disease

During the 5th Targeting Microbiota World Congress 2017, Dr. Marcus Claesson from University College Cork, Ireland will present his study related to "The microbiota, epigenome and transcriptome of colonic inflammation in inflammatory bowel disease”

Previous studies of inflammatory bowel disease (IBD) have yielded inconclusive results for the composition and relationship between the microbiota and topographic distribution of inflammation. Dr Claeson's team examined paired biopsies from inflamed and non-inflamed segments of colonic mucosa from a large number of IBD patients and healthy controls using high throughput sequencing for microbiota composition and host/microbe expression, and bead arrays for host genetic and epigenetic analyses. Their findings confirmed some previous knowledge and also added new insights into the role of the host epigenome and transcriptome and their interactions with the mucosal microbiota.

For more information about Targeting Microbiota Congress, which will be held in Berlin on October 26-27, 2017: www.microbiota-site.com