Dr. Jakob Zimmermann, University of Bern, Switzerland will highlight "Novel techniques in microbiota research: From meta-omics to single cells" during Targeting Microbiota World Congress 2017.
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According to Dr Jakob Zimmermann: "Recent advances in next generation sequencing have vastly increased our knowledge about composition and functional potential of the intestinal microbiota.
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While meta-genomic and -transcriptomic approaches have provided fundamental new insight into host-microbiota mutualism, they do not deliver information on the single cell level or allow for further functional, e.g. metabolomic characterization of the bacteria.
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In my talk, I will briefly summarize recent developments in alternative, complementary approaches, such as cultivating previously “unculturable” bacteria. In particular, I will introduce our novel approach of FACS-sorting viable bacteria from a defined murine intestinal microbiota based on genome size and light-scattering for downstream functional and metabolomic analyses."
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