Recent advances on the relation between the microbiome-gut-brain axis and the neurodegenerative diseases

Maria Cecilia Giron from University of Padova, Italy will talk about "Recent advances on the relation between the microbiome-gut-brain axis and the neurodegenerative diseases" during the  6th World Congress on Targeting Microbiota 2018 Congress.

"In the last decade, emerging evidence has revealed the presence of an intense dialogue between the brain and the gastrointestinal system, the so-called brain-gut axis. Disruption of this complex relationship has been shown to be associated to the pathogenesis of several disorders, ranging from irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD), to depression, anxiety, dementia and Parkinson’s disease.

We have demonstrated that gut dysbiosis affects functional and structural integrity of the enteric nervous system. We are currently examining a potential microbiota-gut-brain axis involved in neuroplasticity and neurodegeneration. Deciphering the interactive dialogue that occurs between microorganisms in the gut and the activity of the immune system regulated by Toll-like receptors is crucial for the discovery and the development of compounds such as pharma- and nutraceuticals (including syn-, pre- and probiotics), critical for preserving or restoring homeostasis in the gut as well as in the central nervous system."

Targeting Microbiota 2018
www.microbota-site.com