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Best Short Oral Presentation Awards 2021
35 Short Oral Presentations were communicated during the 8th World Congress on Targeting Microbiota 2021, held on October 20-22.
The scientific committee nominated 7 presentations for the Best Short Oral Presentation Awards of 2021:
Postbiotic Metabolite - Uroloithin A as a Lead Molecule for Atopic Dermatitis
Sebastian Granica, Medical University of Warsaw, Poland
Biotransformation of the Constituents of Medicinal Plants Used in the Urinary Tract Infections by Human and Pig Gut Microbiota
Dominik PopowskI, Medical University of Warsaw, Poland
Synthetic Derivatives of Urolithin A Increase CACO-2 Monolayer Integrity, Impede Intestinal Glucuronidation, and Suppress TNF Alpha Production in THP-1 Derived Macrophages
Maciej Korczak, Medical University of Warsaw, Poland
Generation of Microbial Compositions From 16S rRNA Sequences — Are You Generating Medically Meaningful Analyses?
Eric Nayman, Herbert Wertheim College of Medicine, USA
A Systematic Review on the Latest Development of Probiotics Intervention as Prevention and Therapy for Covid-19 Infection
Learn-Han Lee, Monash University Malaysia, Malaysia
Gut Microbiome Predicts Clinically Important Improvement in Patients with Rheumatoid Arthritis
Jaeyun Sung, Mayo Clinic, USA
Probiotic Supplementation and Micronutrient Status in Healthy Subjects: A Systematic Review of Clinical Trials
Ahmad Saedisomeolia, McGill University, Canada
Winners of the Best Short Oral Presentations - Targeting Microbiota 2021
Postbiotic Metabolite - Uroloithin A as a Lead Molecule for Atopic Dermatitis - Sebastian Granica, Medical University of Warsaw, Poland
Gut Microbiome Predicts Clinically Important Improvement in Patients with Rheumatoid Arthritis - Jaeyun Sung, Mayo Clinic, USA
In the years ahead, Dr. Sung's research group will continue working on ways to apply personalized microbiome data for disease diagnostics and predictive analytics.
Generation of Microbial Compositions From 16S rRNA Sequences — Are You Generating Medically Meaningful Analyses? - Eric Nayman, Herbert Wertheim College of Medicine, USA
“As we are becoming increasingly aware of the vital role that indigenous human microbiota plays in regulating host health and behavior, we must improve our ability to prove causality in this relationship, which is what I intend to keep contributing toward.”
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Interactive Online
www.microbiota-site.com
Best Poster Presentation Awards 2021
Out of 24 Poster Presentations communicated during Targeting Microbiota 2021, the scientific committee nominated 7 posters for the Best Poster Presentation Awards of 2021:
Dietary Supplementation with Spray-Dried Porcine Plasma Has Prebiotic Effects on Gut Microbiota in Senescent Mice
Cristina Rosell-Cardona, Universitat de Barcelona, Spain
The Impact of Early-Life Antibiotic Exposure on the Behaviors and Gut Microbiota in Mice
Yuan Yuan Lin, Cheng Kung University, Taiwan
Gut-Derived Indole-3-Propionic Acid May Modulate the Mitochondrial Organization in Hepatic Stellate Cells
Mariana Ilha, University of Eastern Finland, Finland
Selection of Psychobiotic Microorganisms and Development of a Dietary Supplement with Potential Effect on Mental Health
Melania Casertano, University of Naples Federico II, Italy
Research on Natural Products Applied in Anxiety and Mood Disorders with Regard to Gut Microbiota
Aleksandra Gorczyńska, Medical University of Warsaw, Poland
The Probiotic Yeast Saccharomyces boulardii CNCM I-745 Prevents Invasion of Vaginal Epithelial Cells by Candida albicans and Gardnerella vaginalis
Philippe Tixador, Biocodex, France
Gut Microbiota-Mediated Glucagon-Like Peptide-1 Modulates Locomotor Activity via Vagal-Dependent Pathway
Tzu-Ting Lai, National Cheng Kung University, Taiwan
Winners of the Poster Presentations - Targeting Microbiota 2021
Gut-Derived Indole-3-Propionic Acid May Modulate the Mitochondrial Organization in Hepatic Stellate Cells - Mariana Ilha, University of Eastern Finland, Finland
“Receiving this award was very nice and gives me more energy and confidence to continuous my research about the influence of the gut derived metabolite indole-3- propionic acid in mitochondrial function and future possible compound for the resolution of liver fibrosis”
Dietary Supplementation with Spray-Dried Porcine Plasma Has Prebiotic Effects on Gut Microbiota in Senescent Mice - Cristina Rosell-Cardona, Universitat de Barcelona, Spain
"Currently, my research is focused on the effects of spray-dried plasma proteins on microbiota composition and its neuroprotective effects against Alzheimer’s disease hallmarks in senescent mice. Next year, I would like to study if these effects are linked through the gut-brain axis. Personally, I am about to finish my PhD and I am looking forward to finding new opportunities to develop my research career, improve my skills, and look deeply into the gut-brain axis field."
The Probiotic Yeast Saccharomyces boulardii CNCM I-745 Prevents Invasion of Vaginal Epithelial Cells by Candida albicans and Gardnerella vaginalis - Philippe Tixador, Biocodex, France
“For the next year, we would like to complete this study notably by characterizing the mechanisms which promote the beneficial effects of S.boulardii CNCMI-745 in the treatment of the vulvovaginitis and publish all these data in a peer-to-peer scientific journal.”
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Interactive Online
www.microbiota-site.com
Scientific Awards of Targeting Microbiota 2021
Targeting Microbiota 2021 was successully held on October 20-22 2021, as an Interactive Online meeting.
At the end of the congress, the scientific committee decided to award some speakers for their excellent contribution.
Scientific Award #1
After an excellent and special talk about "Microbiota Transfer Therapy for Autism: Multi-Omic Approaches and Lessons Learned", Dr. Rosa Krajmalnik-Brown was discerned the Trageting Microbiota 2021 Scientific Award.
Dr. Krajmalnik-Brown gave an overview on her achievements and perspective in Autism Disorders. She is the director of the Biodesign Center for Health Through Microbiomes and a Professor at the School of Sustainable Engineering and The Built Environment, at Arizona State University, USA.
She is a pioneer in research on gut microbiome and autism. She is author of 4 patents and more than 115 peer-reviewed publications. Dr. Krajmalnik-Brown specializes on molecular microbial ecology for bioremediation, the use of microbial systems for bioenergy production, and the human intestinal microbial ecology and its relationship to obesity, bariatric surgery, metabolism, and autism.
Scientific Award #2
Dr. Aleksander Kostic was also the winner of a scientifc award for his presentation about Reconstruction of Ancient Microbial Genomes from the Human Gut.
Dr. Aleksandar Kostic along with his team have shown that industrial lifestyles are correlated with both a lower diversity in the gut microbiome and increased incidence of chronic diseases, such as obesity and autoimmune diseases. Examining our ancestral gut microbiome may provide insights into aspects of human–microbiome symbioses that have become altered in the present-day industrialized world. Reconstruction of metagenome-assembled genomes (MAGs) is an emerging approach to recover high-quality genomes and previously undescribed species-level genome bins (SGBs) from shotgun metagenomics data. Sequencing reads are de novo assembled into contiguous sequences (contigs), and contigs are binned to form draft genomes.
Scientific Award #3
Prof. Siew Ng gave a presentation on The Promise of Microbiota Modulation during COVID-19 Pandemic, for which she was discerned a scientific award.
Siew Ng is Director of Microbiota I-Center (MagIC) of the Chinese University of Hong Kong. She and her team were the first to report the role of the gut microbiome in COVID-19 and they have developed a novel microbiome immunity consortia to hasten recovery and restore dysbiosis in COVID-19 and its sequele leading to global impact.
Animal Microbiota Symposium Scientific Award
During the session on Targeting Animal Microbiota Symposium, Dr. Andres Gomez was discerned a scientific award for his presentation on
This study, in collaboration with Dr Krishona Martinson- University of Minnesota, was initially conducted to asses whether a reduced lignin (RL) version of alfalfa (8% less compared with the standard version (SV)) improved feed digestibility in horses. The data showed that the incorporation of RL alfalfa in horse diets increased apparent dry matter digestibility; but did not change mean fecal particle size, apparent crude protein digestibility, or mean retention time. When analyzing the fecal microbiome of the horses, when shifting from RL to SV of alfalfa, there were no apparent changes. However, we realized that each horse had a unique microbiome, which responded in an individual and significant manner to the content of lignin in alfalfa. These horse-unique patterns also correlated with individual outcomes in other feed digestibility traits, such as apparent dry matter digestibility and mean fecal particle size, all of which fluctuated differently in each horse. The study shows that horses have highly individualized microbiomes, which may determine individual responses to different types of feed. In other words, dietary interventions in horses trigger individualized microbiome responses, and hence the effects and benefit of some diets ands ingredients may be horse-specific. These results open the door to consider individualized nutrition strategies in companion and food animals.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Interactive Online
www.microbiota-site.com
Microbiota Transfer Therapy for Autism: Multi-Omic Approaches and Lessons Learned
The International Society of Microbiota is pleased to invite Dr. Rosa Krajmalnik-Brown to provide an Inaugural talk on "Microbiota Transfer Therapy for Autism: Multi-Omic Approaches and Lessons Learned". Dr. Rosa Krajmalnik-Brown will overview her achievements and perspective in Autism Disorders. She is the director of the Biodesign Center for Health Through Microbiomes and a Professor at the School of Sustainable Engineering and The Built Environment, at Arizona State University, USA.
Role of Microbiota-Gut-Brain Axis Dysfunctions Induced by Infections in the Onset of Anorexia Nervosa
Dr. Marie Galmiche, from Normandie University, France, will join Targeting Microbiota 2021.
Dr. Galmiche will give a talk about "Role Of Microbiota-Gut-Brain Axis Dysfunctions Induced by Infections in the Onset of Anorexia Nervosa"
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Tryptophan Metabolism in Gut Microbes and Brain Axis
Prof. Wei-Yun Zhu from College of Animal Science and Technology, Nanjing Agricultural University, China will join the Targeting Microbiota 2021 congress which will be held on October 20-22, 2021 and will provide a talk concerning "Tryptophan Metabolism in Gut Microbes and Brain Axis".
Prof. Zhu confirms that the bilateral communication network between the gastrointestinal (GI) tract and the central nervous system is regards as the gut-brain axis (GBA). Tryptophan is important for the growth and health of the animal and humans, and its microbial metabolism affects the interaction between gut microbiota and the GBA. By employing intestine cannulated pig model and adopting hindgut microbiota-targeting approaches either using antibiotics or increasing carbohydrate level, together with mechanistic studies in mice and neuronal cells, she demonstrates that tryptophan, and also another aromatic amino acid tyrosine, circulating in the gut, blood and brain, act as mediators between hindgut microbiota and brain neurochemistry.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
What Can the Microbiota of the Naked Mole-Rat Tell Us – The Clue to Longevity
Prof. Gerd Birkenmeier from the University of Leipzig, Germany, will join the Targeting Microbiota 2021 Congress and will give a presentation entitled "What Can the Microbiota of the Naked Mole-Rat Tell Us – The Clue to Longevity".
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Exosomes and Microbiota: Recent Advances and Perspectives
Dr. Duncan Ross and Dr. Rainer Mutschler from Biomedical Center Speyer, Germany, will talk about Exosomes and Microbiota: Recent Advances and Perspectives.
They both confirm that exosomes, or extracellular vesicles, are nanometer lipid vesicles known to be secreted by most eukaryotic and prokaryotic cell types. Additionally, it is well known that germ free animal models lacking commensal bacteria are prone to food allergies among other types of dysfunction. The production of extracellular vesicles by gram negative and gram positive bacteria is recently being understood and are classified as outer membrane vesicles when released by Gram-negative bacteria or as membrane vesicles when released by Gram-positive bacteria. In some models, bacterial EVs alone can induce regulatory T cell formation potentially tolerizing the host to these foreign antigens. The isolation and more importantly, characterization, of these small vesicles is a rapidly evolving field. Methods such as dSTORM, High performance liquid chromatography, RNA characterization and the use of known control EVs are all critical to the creation of reproducible exosome products. Bacterial EVs can interact with host cells through three mechanisms: (1) direct activation of host receptors; (2) delivery of bacterial EV content; and (3) full incorporation of EVs into the host cell cytoplasm. TLR activation and downstream signaling will be discussed in the context of host immune responses, as well as methods of GMP manufacturing of same.
Other Speaker in the session:
Dr. Rainer Mutschler, Biomedical Center Speyer, Germany
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Interactive Online Congress
www.microbiota-site.com
Reconstruction of Ancient Microbial Genomes from the Human Gut
It is a great pleasure to announce you that Dr. Aleksandar Kostic from Harvard Medical School, USA will give a keynote talk during the Targeting Microbiota 2021 about his excellent study published in Nature concerning the "Reconstruction of Ancient Microbial Genomes from the Human Gut".
The ISM Scientific Committee stated that "Dr. Aleksandar Kostic's study is one of the most excellent study published this year".
Critical Evaluation of Faecal Microbiome Preservation using Metagenomic Analysis
The Organizing Committee of Targeting Microbiota 2021 Congress is honored to announce the particpation of Dr. Alena Pribyl from Microba, USA.
Dr. Pribyl will present their recent investigation on "Critical Evaluation of Faecal Microbiome Preservation using Metagenomic Analysis".
Additionally, she recently published a related article in Nature about their study.
Dr. Pribyl demonstrates that accurate preservation of faecal samples is critical as more studies seek to use the gut microbiome to identify biomarkers of disease. In her research, she undertakes an in-depth evaluation of faecal preservation methods using shotgun metagenomics to identify the best methods for use at room temperature. These methods included RNALater, OMNIGene-GUT, a dry BBL swab, LifeGuard, and a novel method for preserving faecal samples, a Copan FLOQSwab in an active drying tube (FLOQSwab-ADT). Along with her team, she further evaluated the best performing method, the FLOQSwab-ADT, at various temperatures to determine its range of use and found it maintained its performance across all temperatures.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Honeybees Microbiome: Recent Advances and Perspective on Compartmentalization in the Adult Gut
Prof. Daniele Daffonchio, from King Abdullah University, Saudi Arabia, will join us at the 8th World Congress on Targeting Microbiota.
Prof. Daffonchio will talk about "Honeybees Microbiome: Recent Advances and Perspective on Compartmentalization in the Adult Gut", mainly focuing on the microbial components of forager honeybees and their compartmentalization along the gut protions. Prof. Daffonchio will explain the results of his studies and the observed changes in the distribution and abundance of microbial components in the gut.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Microbial Endocrinology as a Framework for understanding the Avian Microbiome in a Post-Antibiotic World
Dr. Joshua Lyte from USDA Agricultural Research Service, USA will join the Targeting Microbiota 2021 Congress and will give a presentation entitled "Microbial Endocrinology as a Framework for Understanding the Avian Microbiome in a Post-Antibiotic World".
In his talk, Dr. Lyte will highlight about: The poultry industry has supplemented feed with antibiotics for decades in order to improve avian growth performance, maintain intestinal health, and suppress colonization by foodborne pathogens that cause severe diseases in human consumers. With this decades-old practice of antibiotic feed supplementation rapidly coming to an end, the poultry industry is examining how the microbiome can be harnessed to promote intestinal health and prevent colonization by foodborne pathogens. The evolutionary, neurochemical-based, cross-talk between the microbiome and the host, known as microbial endocrinology, provides a framework to elucidate the mechanisms by which the microbiome influences poultry health and exclusion of foodborne pathogens. As members of the microbiota both produce and recognize the same neurochemicals that are produced by the host’s intestinal nervous system and enteroendocrine cells, use of a microbial endocrinology-based context represents a unique approach to identify relevant mechanisms as well as design interventions to promote poultry health, and ultimately human health as well.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Microbiota regulate social behavior via stress response neurons in the brain
Dr. Wei-Li Wu from California Institute of Technology, USA will join the Targeting Microbiota 2021 Congress and give a presentation entitled "Microbiota regulate social behavior via stress response neurons in the brain".
This talk will be about: The microbiome modulates neuronal activity in specific brain regions of mice to regulate canonical stress responses and social behaviours. Specific gut bacteria can restrain the activation of the hypothalamus-pituitary-adrenal axis. The microbiome can affect social behaviours through discrete neuronal circuits that mediate stress responses in the brain.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Fecal Microbiota and Metabolite Profiles in IBD and IBS
Prof. Lena Öhman from University of Gothenburg, Sweden will join the Targeting Microbiota 2021 Congress and will give a presentation entitled "Fecal Microbiota and Metabolite Profiles in IBD and IBS".
Prof. Öhman's research group is successfully focusing on describing gut microbiota, immune profile and the link to disease profile, as well as therapy outcome in patients with inflammatory bowel disease (IBD) and patients with with irritable bowel syndrome (IBS).
Patients with inflammatory bowel disease suffer from a chronic inflammation of the intestinal tract. The aetiology of the intestinal inflammation is still unknown but is thought to arise due to a dysregulated immune response to gut microbiota. The disease cannot be cured, although many IBD patients benefit from antibody therapy, but the effect is highly variable and at least 30% of the patients undergoing this treatment experience no clinical improvement. Today, it is not possible to predict the patients’ disease course or response to biological therapy. Hence, there is an urgent need for biomarkers predicting clinical disease course and therapeutic outcome in patients with IBD.
Irritable bowel syndrome (IBS) is considered to be one of the most frequent clinical problems in gastroenterology with an estimated prevalence in the community between 10 to 25 %. Despite the high frequency, effective therapeutic strategies for IBS are limited with average therapeutic gains over placebo and there is a clear unmet medical need for treating IBS.
We hypothesize that gut microbiota and the immune system influence disease course and therapeutic outcome in the patients with IBD and IBS, respectively. The aim of this project is therefore to establish how gut microbiota and immune activity influence disease course and identify microbiotic and immunological indicators of therapy outcome.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
The Promise of Microbiota Modulation during COVID-19 Pandemic
Prof. Siew C Ng from The Chinese University of Hong Kong will present her recent study entitled "The Promise of Microbiota Modulation during COVID-19 Pandemic".
During her presentation, Prof. Ng will present new data on impact of gut microbiota on post acute covid syndrome and the role of targeted microbiota modulation during SARS Cov2 Pandemic, and its relationship with COVID-19 vaccination.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Nonlinear Machine Learning Pattern Recognition and Bacteria-Metabolite Multilayer Network Analysis of Perturbed Gastric Microbiome
Dr. Carlo V. Cannistraci from Tsinghua University, China will give a presentation entitled "Nonlinear Machine Learning Pattern Recognition and Bacteria-Metabolite Multilayer Network Analysis of Perturbed Gastric Microbiome".
During his presentation, Dr. Carlo V. nistracCani will state that the stomach is inhabited by diverse microbial communities, co-existing in a dynamic balance. Additionally, long-term use of drugs such as proton pump inhibitors (PPIs), or bacterial infection such as Helicobacter pylori, cause significant microbial alterations. Yet, studies revealing how the commensal bacteria re-organize, due to these perturbations of the gastric environment, are in early phase and rely principally on linear techniques for multivariate analysis. In this talk, he discloses the importance of complementing linear dimensionality reduction techniques with nonlinear ones to unveil hidden patterns that remain unseen by linear embedding. Then, he proves the advantages to complete multivariate pattern analysis with differential network analysis, to reveal mechanisms of bacterial network re-organizations which emerge from perturbations induced by a medical treatment (PPIs) or an infectious state (H. pylori). Finally, he shows how to build bacteria-metabolite multilayer networks that can deepen our understanding of the metabolite pathways significantly associated to the perturbed microbial communities.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
The Horse Gut Microbiome Responds in a Highly Individualized Manner to Forage Lignification
Dr. Andres Gomez from University of Minnesota-Twin Cities, USA will join the Targeting Animal Microbiota Symposium and give a presentation entitled "The Horse Gut Microbiome Responds in a Highly Individualized Manner to Forage Lignification".
In this talk, Dr. Gomez will show how different horses harbor unique fecal microbiomes, which are modulated in a horse-specific manner upon dietary changes. Specifically, that when the percent of lignin is changed in forage, the equine gut microbiome is not modulated in the same way across different individuals. Instead, each horse microbiome reacts differently to the same dietary change.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Role of microbiome in cardiometabolic health
Dr. Noel T. Mueller from Johns Hopkins University Bloomberg School of Public Health, USA will join the Targeting Microbiota 2021 congress and will present his recent study on Role of microbiome in cardiometabolic health.
Dr. Mueller will also highlight the Effects of metformin on microbiome and metabolites.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Real-time monitoring of ruminal microbiota reveals their roles in dairy goats during subacute ruminal acidosis
Dr. Shengru Wu, Associate professor of Northwest A&F University, China will join the Targeting Microbiota 2021 Congress which will be held on October 20-22, 2021 and give a presentation entitled "Real-time monitoring of ruminal microbiota reveals their roles in dairy goats during subacute ruminal acidosis".
Summary of Talk: Ruminal microbiota changes frequently with high grain diets and the occurrence of subacute ruminal acidosis (SARA). Significant bacterial differences between goats from the SARA and healthy groups are identified at every hour for six continuous hours after feeding, and 29 common differential genera between two groups over 6 h after feeding are all related to the altered pH and lipopolysaccharides. Transplanting the microbiota from donor goats with SARA could induce colonic inflammation in antibiotic-pretreated mice. Overall, significant differences in the bacterial community and rumen fermentation pattern between the healthy and SARA dairy goats are real-time monitored, and then tested using ruminal microbe transplantation to antibiotic-treated mice.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
The Eubiotic Potential Of Tannins In Piglets' Nutrition
Dr. Jakub Piwowarski from Medical University of Warsaw, Poland. Dr. Piwowarski will present his recent study entitled The Eubiotic Potential Of Tannins In Piglets' Nutrition.
Tannins are commonly considered as anti-nutritional factors in piglets' nutrition. On the other hand, certain tannin-containing plants are well known for their anti-diarrheal properties, which have been utilized since ancient times in human and veterinary medicine but had been superseded by antibiotics, since discovery of penicillin in 1928 and introduction of antimicrobials in farm animal production since the 1950s. Enterotoxigenic Escherichia coli (ETEC)- induced diarrhoea in piglets is one of the most important health conditions in pigs farming. Decades of extensive antibiotics use in prevention and therapy of infections in animals significantly contributed to the spread of antimicrobial resistance, leading to the restrictions on their use in farm animals. As the consequence, the development of novel preventive and therapeutic strategies targeted on maintaining piglets gut health, which are based on pleiotropic mechanisms, is urgently needed.
The conducted studies have shown that selected tannin-rich plant formulations are able to significantly inhibit the ETEC growth and its adhesion to intestinal epithelial cell monolayers. The relevant stimulation of IPEC-J2 epithelial cells monolayers formation through enhancement of tight junction proteins production was also observed. Despite the determined anti-ETEC properties, the tested tannin sources did not negatively affect alpha diversity and metabolism of intestinal microbiota of post-weaning piglets ex vivo. Certain changes in microbial taxa abundances were induced, some of which correlated with the formation of postbiotic metabolites, namely urolithins, which proven anti-inflammatory properties can be beneficially contribute to gut health of piglets during the weaning period.
The conducted studies support the historically attributed anti-diarrheal properties of tannin-containing plant preparations revealing their eubiotic effects, that not only respect the ecological context of preserving the homeostasis of intestinal microbiota but also support the intestinal epithelium development in post-weaning piglets. The obtained results serve as an initial point for further studies on development of novel, sustainable feed additives dedicated to farm animals being scientifically based alternatives to antibiotics.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
Linking Lactic Acid Bacteria from Food with the Gut Microbiome
Dr. Edoardo Pasolli, from University of Naples Federico II, Department of Agricultural Sciences, Italy, will join the Targeting Microbiota Congress which will be held on October 20-22, 2021 and will present a talk entitled "Linking Lactic Acid Bacteria from Food with the Gut Microbiome".
According to his latest researches, he confirms that large quantities of live lactic acid bacteria are consumed within fermented foods, but it is not yet known to what extent the LAB they ingest become members of the gut microbiome. By analysis of almost ten thousand metagenomes from human samples, Dr. Pasolli shows that the prevalence and abundance of LAB species in stool samples is generally low and linked to age, lifestyle, and geography. Moreover, we demonstrate that closely related LAB strains occur in both food and gut environments and provides unprecedented evidence that fermented foods can be indeed regarded as a possible source of LAB for the gut microbiome.
Targeting Microbiota 2021 Congress
October 20-22, 2021 - Paris, France & Online
www.microbiota-site.com
